ABSTRACT
Globally, herbal therapy is still the backbone of about 80% of the population in developing countries as essential healthcare, because the herbals are cheapest, widely available anywhere, and with no side effects. Many of Western medicines have been derived from plant resources, e.g., magnaprin from bark of willow, dioxin from foxglove, qualaquin from cinchona bark, and zomorph from the opium poppy. Scientists, doctors, and pharmaceutical companies have access to information on herbal medicines; however, the main issue is the absence of scientific validation. The mode of action of many plant-derived methodologies can be negatively affected by the isolation technique, concentration, time, and administrative route, lack of uniform formulation within or among manufacturers. In addition, the efficiency of herbal medicine may be due to symbiotic activity of multi-pace bio-compounds and antagonist actions, so that testing of single bio-compound may not be an appropriate evaluation of the efficiency of the “crude” extracts used by patients. Phyto-chemicals in the form of dietary supplements, herbs, and spices, comprise an unlimited source of molecules available for improving human health. The claimed beneficial values of the described species give a sound basis for the significant role of folk medicine in the development of new drug.
Further insights on the mechanisms of action for different herbals and their bioactive compounds are necessary to discover the molecular targets for human diseases. Such mastery will help to enlighten specialists, permit them to give exceptional guidance to their patients and thus 4can support in the improvement of innovative pharmaceuticals via a rediscovery of age-old compounds. For example, the biocompounds in the fennel plant can be used for different drug formulations, which play a significant role in our health. Majority of studies were mainly conducted on the anti-oxidant, antimicrobial activities in different animal models. Natural products have traditionally been favored for the exploration of potential targets for drug production, and its function is still clear today. The pharma-industry has been facing a serious threat as the drug discovery practice is becoming exceptionally costly, sensitive, and typically ineffective. Natural materials may serve as the main source of drugs and more than half of the pharma preparations in use today are derived from natural plant resources. However, careful experimental designs using multidisciplinary pathways together with consistency and assessment of natural products are important for the successful production of innovative and promising therapies.
