ABSTRACT
Renal cancer is one of the most common urological malignancies, and early diagnosis and treatment is important, as once metastasised, five-year survival rates remain poor. Minimally invasive ablative therapies including cryotherapy have an emerging role in patients unfit for surgery. High intensity focused ultrasound ablation of renal tumours offers an alternative non-invasive treatment strategy, and a variety of device designs have demonstrated pre-clinical and clinical capabilities, with early trials demonstrating promise for clinical translation. The clinical efficacy of this approach is likely to be improved with further technological advances and potentially the use of high-frequency jet ventilation to mitigate against respiratory movement.
