ABSTRACT
Moderate Parkinson’s disease (PD) can be defined as the phase of the illness that occurs when PD symptoms are no longer completely controlled, and complications of drug therapy and disease progression emerge. This phase includes the appearance of motor fluctuations and dyskinesias, the initiation of adjunctive therapy, and the emergence of many nonmotor symptoms. The moderate phase of PD may encompass years of illness and usually represents the longest phase of an individual’s battle with PD. During this period, appropriate care often involves frequent follow-up with regular adjustments of the medical regimen, a reliance on rational polypharmacy, referral to movement disorder specialists, and the use of the myriad of ancillary health services.
