ABSTRACT

Since the original description of the “Shaking Palsy” by James Parkinson in 1817, knowledge about Parkinson’s disease (PD) made slow progress for over a century. Beginning in the late 1950s, our understanding of PD has progressed by leaps and bounds, largely through the advent of better biomedical technology and extraordinary progress in allied medical disciplines such as neuropharmacology, neurochemistry, neuropathology, molecular biology, and genetics. The advances made thus far can be discussed from the broad perspectives of etiopathogenesis and management.